COROSOLIC ACID

Synonyms. Corosolic acid; 2alpha-Hydroxyursolic acid; Colosolic acid; Corsolic acid; Glucosol; (2alpha,3beta)-2,3-Dihydroxyurs-12-en-28-oic acid; (1S,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)- 10,11-Dihydroxy-1,2,6a,6b, 9,9,12a-heptamethyl- 2,3,4,5, 6,6a, 7,8,8a,10,11,12,13, 14b-tetradecahydro -1H- picene-4a-carboxylic acid;

COROSOLIC ACID

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

4547-24-4

EINECS RN

 

FORMULA

C30H48O4

MOLE WEIGHT

472.70

H.S CODE

2918.19.9000

SMILES

C1[C@H]([C@@H](C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5 (C (= O)O) CC[C@@H](C)[C@@H](C)[C@H]5C4=CC[C@H]3[C@@]12C) O)O

CLASSIFICATION

Triterpenoid

EXTRA NOTES

Corosolic acid is a pentacyclic triterpene acid, found in Lagerstroemia speciosa, used in dietary supplements as a glucose-lowering agent and insulin mimetic. It is similar in structure to ursolic acid, differing only in the fact that it has a 2-alpha-hydroxy attachment.(Wikipedia)
A natural product found particularly in Rhododendron species and Eriobotrya japonica.(ChEBI)

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

yellow to green powder

MELTING POINT

243 ~ 245 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

Partially soluble

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents.

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Corosolic acid

Google Scholar Search - Corosolic acid

Drug Information Portal (U.S. National Library of Medicine) - Corosolic acid

PubChem Compound Summary - Corosolic acid

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Corosolic acid

http://www.ebi.ac.uk/ - Corosolic acid

http://www.ncbi.nlm.nih.gov/ - Corosolic acid

 

SALES SPECIFICATION

APPEARANCE

yellow to green powder

ASSAY

98.0% min (on anhydrous basis)

LOSS ON DRYING

5.0% max

HEAVY METALS

20ppm max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD CLASS

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

May be harmful if inhaled. May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. May cause eye irritation. May be harmful if swallowed.

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

26-36

 

PACKING

Preserve in light-resistant and well-closed containers